Fueling the Brain's Marathon: How Myelin Powers Endurance Athletes

Fueling the Brain's Marathon: How Myelin Powers Endurance Athletes

Daniel Hall 01/11/2023
Fueling the Brain's Marathon: How Myelin Powers Endurance Athletes

In the world of endurance athletes, where every ounce of energy is precious, a remarkable discovery has emerged.

Marathon runners, pushing their physical limits over grueling distances, may be drawing energy from an unlikely source – myelin, the fatty tissue surrounding nerve fibers. Recent findings suggest that during the intensity of a marathon race, this insulation material becomes a vital fuel for the brain. While the notion may sound unconventional, brain scans of marathon runners indicate that this energy source undergoes significant fluctuations immediately post-race. Two weeks after the marathon, the levels of brain fat return to nearly pre-race conditions, highlighting the role myelin may play in sustaining cognitive function during exhaustive physical exertion.

Myelin: More Than Just Insulation


At first glance, myelin is often perceived as a static insulation material, much like rubber encasing an electrical wire. Its primary function is to facilitate high-speed communication between nerve cells, a critical process for optimal brain function. However, recent insights suggest that myelin is far from inert. This dynamic structure, known as myelin plasticity, exhibits changes in size and abundance influenced by varying cellular conditions. This phenomenon challenges the long-standing belief that myelin remains unchanged once it's formed.

Research has shown that the fatty molecules and other components within myelin undergo regular turnover, deconstructing the insulating material and reconstructing it. Notably, studies conducted on mice have revealed that brain cells can tap into these internal fat reserves when the brain's typical energy source, sugar, is scarce.

Myelin's Role in Sustaining Endurance

Driven by his curiosity about how the brain continues to function after strenuous exercise depletes the body's energy reserves, Carlos Matute, a neurobiologist and marathon runner, embarked on an intriguing study. He sought to investigate whether the fats within myelin could potentially serve as a source of energy for the brains of endurance athletes. To explore this idea, his research team employed magnetic resonance imaging (MRI) to scan the brains of four marathon runners both before and after their races. A subset of the runners was also scanned two weeks post-race.

The immediate days following the marathon showcased a notable reduction in brain myelin, a sign that the fatty tissue wrapped around nerve fibers had thinned. However, the follow-up scans conducted two weeks later revealed a remarkable rebound of myelin, with it thickening once more around neural fibers. This swift decline followed by rapid recovery presented a striking result that intrigued experts in the field.

Challenges and Skepticism: Brain Function and Recovery

While Matute's findings are thought-provoking, they also invite skepticism and questions. The use of water content between layers of myelin as a proxy for myelin levels raises concerns. Critics suggest that the observed fluctuations could be attributed to dehydration, particularly considering that post-marathon runners might experience reduced hydration levels. However, Matute argues against this notion, asserting that the scanning took place several days after the marathon, allowing participants ample time to rehydrate. The brain volumes of the runners remained relatively consistent before and after the marathon, further challenging the notion of dehydration-induced changes. According to Matute, no evidence suggests brain shrinkage due to dehydration.

Matute's research has raised intriguing possibilities about myelin's role in the energy equation for marathon runners, but many questions remain unanswered. Future investigations aim to explore the impact of this myelin depletion on brain function and the duration required for complete recovery. The results suggest that running is not detrimental to the brain; instead, it prompts the use and replenishment of energy reserves, potentially exercising the brain's metabolic machinery.

Myelin's Dynamic Role in Marathon Performance


In the enthralling world of marathon running, where every step counts, the revelation that myelin, the brain's insulation, might be an energy source brings a new dimension to understanding the power of endurance athletes. While the full extent of myelin's influence on the brain during a marathon is yet to be unraveled, Matute's work has set the stage for further investigations. With marathon running offering not only a physical challenge but also a unique perspective on brain metabolism, this dynamic relationship between myelin and endurance remains an area of compelling research.

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Daniel Hall

Business Expert

Daniel Hall is an experienced digital marketer, author and world traveller. He spends a lot of his free time flipping through books and learning about a plethora of topics.

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