Stephen David Research in Theoretical Neuroscience

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Brain Science | Genetics: Would the Connectome Cure Mental Illness?

Brain Science | Genetics: Would the Connectome Cure Mental Illness?

There is a recent paper, The Connectome of an Insect Brain, submitting a 12-year effort to map the brain of the larval fruit fly, Drosophila melanogaster, showing "3,016 neurons and 548,000 synapses." The high-resolution imaging project was useful to "identifying neuron types, network hubs and circuit motifs."

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Neurobiology: The Consciousness of Organoids, Biocomputers and Artificial Intelligence

Neurobiology: The Consciousness of Organoids, Biocomputers and Artificial Intelligence

There is a recent article, Calm Down. There is No Conscious A.I., making the case that recent advances in artificial intelligence do not make them conscious, since the models do not have feelings, subjective experience and so on. There is another recent article, Scientists Are Growing Mini Brains in the Lab. Are They ... Conscious?, discussing likelihoods for the consciousness of brain Organoids and the ethics.

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 Neuroscience: Does Thought or Memory Require Language?

Neuroscience: Does Thought or Memory Require Language?

Language is a property of the human mind, conceptually.

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Brain Science: Psychedelic Research Skips the Mind for Mental Health

Brain Science: Psychedelic Research Skips the Mind for Mental Health

There is a recent paper, Psychedelics Promote Neuroplasticity Through the Activation of Intracellular 5-HT2A Receptors, on the mechanism underlying psychedelic action for dendritic growth of neurons in the cortex. The study "emphasizes the role of location bias in 5-HT2AR signaling, identifies intracellular 5-HT2ARs as a therapeutic target, and raises the intriguing possibility that serotonin might not be the endogenous ligand for intracellular 5-HT2ARs in the cortex."

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Foreign Accent Syndrome: Brain, Mind or Genetics?

Foreign Accent Syndrome: Brain, Mind or Genetics?

There is a recent paper, Foreign Accent Syndrome as a Heralding Manifestation of Transformation to Small Cell Neuroendocrine Prostate Cancer, stating that, "a man in his 50s with metastatic hormone-sensitive prostate cancer, receiving androgen deprivation therapy and abiraterone acetate/prednisone, presented with an uncontrollable ‘Irish brogue’ accent despite no Irish background, consistent with foreign accent syndrome (FAS). He had no neurological examination abnormalities, psychiatric history or MRI of the brain abnormalities at symptom onset."

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